Dental Technicians' Pneumoconiosis

  • Okamoto Masaki
    Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Japan
  • Tominaga Masaki
    Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Japan
  • Shimizu Shigeki
    Department of Pathology, Kindai University Faculty of Medicine, Japan
  • Yano Chiyo
    Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Japan
  • Masuda Ken
    Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Japan
  • Nakamura Masayuki
    Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Japan
  • Zaizen Yoshiaki
    Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Japan
  • Nouno Takashi
    Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Japan
  • Sakamoto Satoshi
    Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Japan
  • Yokoyama Mitsuru
    Shared-Use Research Center, University of Occupational and Environmental Health, Japan
  • Kawayama Tomotaka
    Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Japan
  • Hoshino Tomoaki
    Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Japan

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Abstract

<p>A 40-year-old female dental technician visited our hospital for the investigation of a chest X-ray abnormality. Chest computed tomography demonstrated centrilobular nodules and lung volume reduction, and her serum KL-6 level was elevated. A histological analysis of the specimens obtained on a surgical lung biopsy showed peribronchiolar fibrosis with pigmented macrophages and cholesterol clefts. An energy-dispersive X-ray analysis showed that these lung tissues contained some metals, including indium. The serum indium level was also elevated. We diagnosed this patient with pneumoconiosis caused by exposure to sandblasting certain dental metals. This is the first reported case of pneumoconiosis in a dental technician associated with exposure to indium. </p>

Journal

  • Internal Medicine

    Internal Medicine 56 (24), 3323-3326, 2017

    The Japanese Society of Internal Medicine

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