Isolation of equine peripheral blood stem cells from a Japanese native horse

• ISHIKAWA Shingo

  Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima 890-0065, Japan

• HORINOUCHI Chie

  Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima 890-0065, Japan

• MIZOGUCHI Ryugo

  Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima 890-0065, Japan

• SENOKUCHI Asuka

  Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima 890-0065, Japan

• KAMIKAKIMOTO Rie

  Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima 890-0065, Japan

• MURATA Daiki

  Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima 890-0065, Japan

• HATAZOE Takashi

  Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima 890-0065, Japan

• TOZAKI Teruaki

  Laboratory of Racing Chemistry, Tochigi 320-0851, Japan

• MISUMI Kazuhiro

  Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima 890-0065, Japan

• HOBO Seiji

  Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima 890-0065, Japan

抄録

The sizes of Japanese native horses have drastically decreased, and protection of these populations is important for Japanese horse culture. Social trials as well as scientific attempts are necessary for maintaining the breed. Mesenchymal stem cells (MSCs) have potential as a cell source for various cell therapies. However, there have been no reports on MSCs of Japanese native horses. We aimed to isolate and characterize MSCs from a Japanese native horse, the Noma horse. Plastic-adherent and self-replicating cells were isolated from a Noma horse’s peripheral blood (PB). The isolated cells had trilineage potential and a surface antigen of mesenchymal cells, so they fulfilled the minimal criteria of MSCs. Therefore, PB can be one source of MSCs for Japanese native horses.

収録刊行物

• Ｊｏｕｒｎａｌ　ｏｆ　Ｅｑｕｉｎｅ　Ｓｃｉｅｎｃｅ

  Ｊｏｕｒｎａｌ　ｏｆ　Ｅｑｕｉｎｅ　Ｓｃｉｅｎｃｅ 28 (4), 153-158, 2017

  日本ウマ科学会

キーワード

• Japanese native horse
• mesenchymal stem cells
• peripheral blood

詳細情報

• CRID: 1390282679347500928
• NII論文ID: 130006251675
• NII書誌ID: AA11010806
• DOI: 10.1294/jes.28.153
• ISSN: 13477501
• ISSN: 13403516
• NDL書誌ID: 028759657
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I028759657
• Web Site: https://www.jstage.jst.go.jp/article/jes/28/4/28_1722/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2018214104
• 本文言語コード: en
• データソース種別:
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  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可