Endovenous Treatment for Acute Massive Pulmonary Thromboembolism

  • Tajima Hiroyuki
    Center for Minimally Invasive Treatment, Nippon Medical School Musashikosugi Hospital
  • Kaneshiro Tadashi
    Center for Minimally Invasive Treatment, Nippon Medical School Musashikosugi Hospital
  • Takenoshita Naoko
    Center for Minimally Invasive Treatment, Nippon Medical School Musashikosugi Hospital
  • Ichikawa Taro
    Department of Radiology, Nippon Medical School Musashikosugi Hospital
  • Isshiki Saiko
    Department of Radiology, Nippon Medical School Musashikosugi Hospital
  • Murata Satoru
    Department of Radiology, Nippon Medical School Hospital
  • Onozawa Shiro
    Department of Radiology, Teikyo University Mizonokuchi Hospital
  • Nakazawa Ken
    Department of Radiology, Saitama Medical University International Medical Center

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<p>Treatment for venous thromboembolic conditions differs significantly depending on whether the condition is acute or chronic. Endovenous treatment is now available for treating the most severe cases of acute massive pulmonary thromboembolism, and the goal is rapid central clot removal to relieve life-threatening pulmonary circulation. Endovenous catheter interventions include catheter-directed thrombolysis and catheter-assisted thrombus removal. The latter is divided into aspiration thrombectomy, fragmentation, and rheolytic thrombectomy. Data from cohort studies indicate that the clinical outcome and safety after open surgical treatment and endovenous treatment may be comparable. This paper reviews the current approaches to endovenous treatment for acute massive pulmonary thromboembolism, and presents our study of hybrid treatment using a combination of local fibrinolysis, mechanical fragmentation, and clot aspiration.</p>

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