Principle and Applications of Wireless Quartz-crystal-microbalance Biosensors

• OGI Hirotsugu

  Graduate School of Engineering, Osaka University

Bibliographic Information

Other Title

• 無線振動子バイオセンサの原理と応用

Abstract

The shear-vibration resonance frequency of an AT-cut quartz crystal shows ultrahigh temperature stability on the order of 1 ppm/K. When molecules are captured on the oscillator surface, the resonance frequency decreases because of the mass-loading effect. Because the shear vibrational mode allows vibration even inside a liquid, the AT-cut quartz resonator has been adopted for biosensors. It has been recognized that the mass sensitivity significantly increases upon thinning the oscillator, but achieving this has never been straightforward because of the heavy electrodes and wires attached directly on the surfaces. We thus developed wireless-electrodeless quartz-crystal-microbalance (QCM) biosensors; instead of electrodes, we used antennas for noncontact measurement of the resonance frequency and achieved significantly improved mass sensitivity. Here, I introduce the principle and configurations of the wireless-electrodeless QCMs, including the MEMS process for mass production.

Journal

• IEICE ESS Fundamentals Review

  IEICE ESS Fundamentals Review 11 (3), 180-185, 2018

  The Institute of Electronics, Information and Communication Engineers

Keywords

• QCM
• wireless
• thinning
• biosensor
• MEMS

Details

• CRID: 1390282680319720448
• NII Article ID: 130006301312
• DOI: 10.1587/essfr.11.3_180
• ISSN: 18820875
• Web Site: https://www.jstage.jst.go.jp/article/essfr/11/3/11_180/_pdf
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed