Terahertz Imaging and Spectroscopy as a Tool for Non-destructive and Non-contact Quality Inspections of Medical Drugs and Polymer Films

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  • SUZUKI Daichi
    Laboratory for Future Interdisciplinary Research of Science and Technology, Tokyo Institute of Technology Research Fellow of Japan Society for the Promotion of Science
  • KAWANO Yukio
    Laboratory for Future Interdisciplinary Research of Science and Technology, Tokyo Institute of Technology

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Other Title
  • テラヘルツ帯電磁波を活用した医薬品・有機膜の非破壊非接触品質分析
  • テラヘルツタイ デンジハ オ カツヨウ シタ イヤクヒン ・ ユウキマク ノ ヒハカイ ヒセッショク ヒンシツ ブンセキ

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Abstract

The development of non-destructive quality inspection methods has been increasingly attracting much attention to ensure the reliability and safety of products, especially in the fields of medicine and materials engineering. In this work, we used terahertz (THz) imaging and spectroscopy as a novel analysis method for in-process quality inspections of medical drugs and polymers. By utilizing advantageous features of THz waves, such as relatively high transmission through objects and THz fingerprint spectra of polymers, we demonstrated non-destructive and non-contact quality inspections, such as the identification of mixtures of medical drugs, the detection of cracks and organic/inorganic contaminations inside multi-layer polymer films, and the evaluation of polymer film thickness. These results indicate that the inspection method based on THz technology can be powerfully used as a quality assurance system.

Journal

  • BUNSEKI KAGAKU

    BUNSEKI KAGAKU 66 (12), 893-899, 2017

    The Japan Society for Analytical Chemistry

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