Chronological evaluation of postoperative nutritional status and quality of life of pancreatic cancer patients

• SATO Naoko

  Department of Oncology Nursing, Tohoku University Graduate School of Medicine

• MOTOI Fuyuhiko

  Department of Surgery, Tohoku University Graduate School of Medicine

• ARIAKE Kyohei

  Department of Surgery, Tohoku University Graduate School of Medicine

• NAKAGAWA Kei

  Department of Surgery, Tohoku University Graduate School of Medicine

• KAWAGUCHI Kei

  Department of Surgery, Tohoku University Graduate School of Medicine

• SATO Masami

  Department of Clinical Research, Innovation and Education Center, Tohoku University Hospital

• KATAYOSE Yu

  Department of Hepato-Biliary Pancreatic Surgery, Tohoku Medical and Pharmaceutical University Hospital

• SATO Fumiko

  Department of Oncology Nursing, Tohoku University Graduate School of Medicine

• UNNO Michiaki

  Department of Surgery, Tohoku University Graduate School of Medicine

Bibliographic Information

Other Title

• 膵癌患者の術後栄養状態とQOLの経時的評価

Abstract

Background: Surgery for pancreatic cancer tends to be extensive and malnutrition due to postoperative stress, reduced exocrine pancreatic function, and impaired gastrointestinal function may affect the quality of life (QOL) of these patients. Objective: To chronologically evaluate the association between postoperative nutritional status and QOL of pancreatic cancer patients and explore ways to improve QOL from a nutritional perspective. Methods: Of 164 recruited patients who underwent surgery for pancreatic cancer, 65 completed preoperative, and 3- and 6-month postoperative nutritional assessment using the Controlling Nutritional Status (CONUT) score and assessment of health-related QOL using the Short Form-36 version 2 (SF-36v₂) Health Survey were included for statistical analysis of correlation between nutritional status and QOL. Results: Pancreatic cancer patients tended to be malnourished before surgery and were generally malnourished 3 months after surgery. Specifically, patients in the pancreatoduodenectomy and total pancreatectomy groups remained malnourished up to 6 months after surgery. Malnutrition was correlated with the QOL domains "Physical Functioning", "Role-Physical", and "Social Functioning". Conclusion: Malnutrition reduces QOL in patients with pancreatic cancer. Improving the nutritional status at 6 months after surgery could be a key to enhance overall QOL.

Journal

• Suizo

  Suizo 32 (6), 873-881, 2017

  Japan Pancreas Society

Keywords

• Pancreatectomy
• Nutritional Status score
• Health-related QOL (HRQOL)

Details

• CRID: 1390282679619405312
• NII Article ID: 130006307404
• DOI: 10.2958/suizo.32.873
• ISSN: 18812805
• ISSN: 09130071
• Web Site: https://www.jstage.jst.go.jp/article/suizo/32/6/32_873/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2018121471
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed