Acute Anorectal Thrombophlebitis Caused by a Protein C Deficiency
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- Eso Yuji
- Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Japan
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- Yoshiji Satoshi
- Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Japan Integrated Clinical Education Center, Kyoto University Hospital, Japan
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- Nakakubo Yuto
- Integrated Clinical Education Center, Kyoto University Hospital, Japan
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- Matsuura Minoru
- Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Japan
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- Seno Hiroshi
- Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Japan
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Abstract
<p>A 46-year-old man visited the emergency department of our hospital with a 3-day history of anal pain, hemorrhaging, and a slight fever. He had previously been diagnosed with protein C deficiency and was prescribed dabigatran, a direct oral anticoagulant. Contrast-enhanced computed tomography showed severe rectal wall thickening with partial defect of enhancement. In addition, sigmoidoscopy revealed a dusky purplish swollen anorectal mucosa just above the dentate line. He was diagnosed with acute anorectal thrombophlebitis, and anticoagulant therapy with heparin was initiated. To our knowledge, this is the first case report of acute anorectal thrombophlebitis caused by protein C deficiency. </p>
Journal
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- Internal Medicine
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Internal Medicine 57 (2), 209-212, 2018
The Japanese Society of Internal Medicine
