Deeper S Wave in Lead V5 and Broader Extent of T Wave Inversions in the Precordial Leads are Clinically Useful Electrocardiographic Parameters for Predicting Pulmonary Hypertension
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- Miura Miyuki
- Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences
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- Ikeda Satoshi
- Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences
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- Yoshida Takeo
- Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences
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- Yamagata Yuki
- Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences
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- Nakata Tomoo
- Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences
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- Koga Seiji
- Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences
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- Koide Yuji
- Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences
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- Kawano Hiroaki
- Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences
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- Maemura Koji
- Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences
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抄録
<p>Electrocardiography (ECG) is used to screen for pulmonary hypertension (PH). However, it is unclear which parameters of ECG are the most useful for screening.</p><p>ECG parameters related to right ventricular hypertrophy criteria were examined in 145 ECGs of subjects who were suspected to have PH and underwent right heart catheterization (RHC) (age 58.4 ± 17.5 years, 112 women, mean pulmonary arterial pressure [MPAP] 35.4 ± 13.3 mmHg). Based on the results of RHC, 108 subjects had PH (56 pulmonary arterial hypertension [PAH] and 52 chronic thromboembolic pulmonary hypertension [CTEPH]).</p><p>Fourteen of 17 ECG parameters in the present study were significantly associated with PH on univariate analysis. On multivariable logistic regression analysis, S wave depth in lead V5 (odds ratio [OR] 1.25, 95% confidence interval [CI] 1.10-1.47) and depth of T wave inversion in lead V4 (OR 1.21, 95% CI 1.03-1.46) were independent predictors of MPAP ≥ 25 mmHg, and the cut-off values determined by receiver operating characteristic curve analyses were 0.42 mV and -0.28 mV, respectively.</p><p>In conclusion, a deeper S wave in lead V5 and the presence of a wider extent of negative T waves in the precordial leads may be clinically simple and useful ECG parameters for screening for PH.</p>
収録刊行物
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- International Heart Journal
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International Heart Journal 59 (1), 136-142, 2018
一般社団法人 インターナショナル・ハート・ジャーナル刊行会