<i>Fusobacterium</i>による化膿性肝膿瘍9症例の臨床的検討―本邦報告例のreview―  [in Japanese] Nine cases of pyogenic liver abscesses caused by <i>Fusobacterium</i>: Review and literature in Japan  [in Japanese]

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Author(s)

    • 重福 隆太 Shigefuku Ryuta
    • 聖マリアンナ医科大学消化器・肝臓内科 Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
    • 奥瀬 千晃 Okuse Chiaki
    • 川崎市立多摩病院消化器・肝臓内科 Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kawasaki Municipal Tama Hospital
    • 鈴木 通博 Suzuki Michihiro
    • 川崎市立多摩病院消化器・肝臓内科 Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kawasaki Municipal Tama Hospital
    • 伊東 文生 Itoh Fumio
    • 聖マリアンナ医科大学消化器・肝臓内科 Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
    • 渡邊 綱正 Watanabe Tsunamasa
    • 聖マリアンナ医科大学消化器・肝臓内科 Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
    • 得平 卓也 Ehira Takuya
    • 聖マリアンナ医科大学消化器・肝臓内科 Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
    • 中野 弘康 Nakano Hiroyasu
    • 聖マリアンナ医科大学消化器・肝臓内科 Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
    • 服部 伸洋 Hattori Nobuhiro
    • 聖マリアンナ医科大学消化器・肝臓内科 Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
    • 池田 裕喜 Ikeda Hiroki
    • 聖マリアンナ医科大学消化器・肝臓内科 Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
    • 松永 光太郎 Matsunaga Kotaro
    • 聖マリアンナ医科大学消化器・肝臓内科 Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
    • 松本 伸行 Matsumoto Nobuyuki
    • 聖マリアンナ医科大学消化器・肝臓内科 Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine
    • 山本 博幸 Yamamoto Hiroyuki
    • 聖マリアンナ医科大学消化器・肝臓内科 Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine

Abstract

<p>自験例と文献的考察より<i>Fusobacterium</i>による肝膿瘍の臨床的特徴を明らかにすることを目的とした.1998年から2017年の20年間で経験した化膿性肝膿瘍125例中,<i>Fusobacterium</i>による肝膿瘍は<i>Fusobacterium necrophorum</i> 1例,<i>Fusobacterium nucleatum</i> 5例,<i>Fusobacterium</i> spp. 3例の計9例であった.年齢の中央値は76歳で男性が多く,背景に腸管疾患,萎縮性胃炎,膵癌,齲歯,咽頭炎がみられたが,糖尿病合併はなかった.他の微生物との混合感染が3例でみられた.<i>Fusobacterium necrophorum</i>による肝膿瘍はLemièrre症候群に続発し,<i>Fusobacterium nucleatum</i>による肝膿瘍では大腸癌を併存する症例がみられた.全例が膿瘍ドレナージと抗菌薬により治療され,予後は良好であった.</p>

<p>The aim of this study is to elucidate clinical features of pyogenic liver abscess (PLA) due to <i>Fusobacterium</i> (F-PLA). We report 9 F-PLA cases together with bibliographic consideration of previously reported in Japan. We diagnosed 9 F-PLA cased (7%) out of 125 PLA cases, from 1998 to 2017. Three cases were due to <i>Fusobacterium species</i>, 1 case was due to <i>Fusobacterium necrophorum</i> and 5 cases were due to <i>Fusobacterium nucleatum</i>. The median age was 76 year-old and male gender was predominated. Underlying diseases were intestinal disease, atrophic gastritis, pancreatic cancer, dental disease and pharyngitis. Notably, 6 cases of <i>Fusobacterium nucleatum</i> PLA with colorectal cancer were reported, and <i>Fusobacterium necrophorum</i> PLA patients are likely to be complicated by Lemièrre's syndrome, suggesting there might be different clinical features among different <i>Fusobacterium</i> species. All cases had good prognosis.</p>

Journal

  • Kanzo

    Kanzo 59(1), 23-32, 2018

    The Japan Society of Hepatology

Codes

  • NII Article ID (NAID)
    130006321670
  • NII NACSIS-CAT ID (NCID)
    AN00047770
  • Text Lang
    JPN
  • ISSN
    0451-4203
  • NDL Article ID
    028781051
  • NDL Call No.
    Z19-130
  • Data Source
    NDL  J-STAGE 
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