Stereocontrolled Total Synthesis of Biologically Active Natural Products

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Other Title
  • 生物活性天然物の立体制御全合成
  • セイブツ カッセイ テンネンブツ ノ リッタイ セイギョ ゼン ゴウセイ

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Abstract

 This review article describes the total syntheses of englerin A, ophiodilactones A and B, marinomycin A, N-methylwelwitindolinone C isothiocyanate, tirandamycins A-D, and tirandalydigin, which possess intriguing biological activities and challenging structures with characteristic ring systems. The focus is on the synthetic methodologies that lead to the highly stereocontrolled assembly of these natural products.<br>

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 138 (2), 191-209, 2018-02-01

    The Pharmaceutical Society of Japan

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