REM睡眠行動障害における筋電図解析  [in Japanese] Electromyography Analysis of Rapid Eye Movement Sleep Behavior Disorder  [in Japanese]

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    • 髙田 宗樹 TAKADA Hiroki
    • 名古屋大学大学院情報科学研究科|福井大学大学院工学研究科知能システム工学専攻 Graduate School of Information Science, Nagoya University|Department of Human and Artificial Intelligence Systems, Graduate School of Engineering, University of Fukui
    • 中山 明峰 NAKAYAMA Meiho
    • 名古屋市立大学病院睡眠医療センター|名古屋市立大学耳鼻咽喉科学 Good Sleep Center Nagoya City University Hospital|Department of Neuro-otolaryngology, Nagoya City University


<p>Polysomnography (PSG), which records physiological phenomena including brain waves, breathing status, and muscle tonus, is useful for the diagnosis of sleep disorders as a gold standard. However, measurement and analysis are complex for several specific sleep disorders, such as rapid eye movement (REM) sleep behavior disorder (RBD). Usually, brain waves during REM sleep indicate an awakening pattern under relaxed conditions of skeletal and antigravity muscles. However, these muscles are activated during REM sleep when patients suffer from RBD. These activated muscle movements during REM, so-called REM without atonia (RWA) recorded by PSG, may be related to a neurodegenerative disease such as Parkinson's disease. Thus, careful analysis of RWA is significant not only physically, but also clinically. Commonly, manual viewing measurement analysis of RWA is time-consuming. Therefore, quantitative studies on RWA are rarely reported. A software program, developed from Microsoft Office Excel<sup>®</sup>, was used to semiautomatically analyze the RWA ratio extracted from PSG to compare with manual viewing measurement analysis. In addition, a quantitative muscle tonus study was carried out to evaluate the effect of medication on RBD patients. Using this new software program, we were able to analyze RWA on the same cases in approximately 15 min as compared with 60 min in the manual viewing measurement analysis. This software program can not only quantify RWA easily but also identify RWA waves for either phasic or tonic bursts. We consider that this software program will support physicians and scientists in their future research on RBD. We are planning to offer this software program for free to physicians and scientists.</p>


  • Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)

    Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) 73(1), 27-33, 2018

    The Japanese Society for Hygiene


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