A clinical case of neosporosis in a 4-week-old holstein friesian calf which developed hindlimb paresis postnatally

• UESAKA Karin

  Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan United Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan

• KOYAMA Kenji

  Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan United Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan

• HORIUCHI Noriyuki

  Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan

• KOBAYASHI Yoshiyasu

  Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan United Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan

• NISHIKAWA Yoshifumi

  National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan

• INOKUMA Hisashi

  Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan United Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan

Abstract

A 4-week-old female Holstein Friesian calf presented with hindlimb paresis. Neurologic examination of spinal reflexes revealed depressed or absent reflexes of the hindlimbs. Menace responses on both sides disappeared on examination of cranial nerves. The calf was finally diagnosed with Neospora caninum infection by pathological findings including nonsuppurative inflammation associated with cysts in the cerebrum and spinal cord. High levels of antibody against recombinant surface antigen 1 of N. caninum (NcSAG1) were detected by ELISA from both serum and cerebrospinal fluid (CSF) samples. This result suggests that detection of antibodies against N. caninum by NcSAG1-ELISA in serum and CSF could be useful for the clinical diagnosis of neosporosis in calves with acquired neurological signs.

Journal

• Journal of Veterinary Medical Science

  Journal of Veterinary Medical Science 80 (2), 280-283, 2018

  JAPANESE SOCIETY OF VETERINARY SCIENCE

Keywords

• astasia
• calf
• NcSAG1-ELISA
• <i>Neospora caninum</i>

Details

• CRID: 1390001206429011200
• NII Article ID: 130006386447
• NII Book ID: AA10796138
• DOI: 10.1292/jvms.17-0205
• ISSN: 13477439
• ISSN: 09167250
• PubMed: 29237996
• Web Site: https://obihiro.repo.nii.ac.jp/records/4241
• Web Site: https://www.jstage.jst.go.jp/article/jvms/80/2/80_17-0205/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2018364264
• Text Lang: en
• Data Source:
  • JaLC
  • IRDB
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed