Effects of <i>Montipora digitata</i> Exoskeleton- derived Aragonite Particles on Human Fibroblasts for Cell Proliferation and Collagen Production <i>in Vitro</i>
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- OKAMURA Tomoharu
- Department of Oral Pathology,
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- TAKEUCHI Tomoki
- Department of Oral Pathology,
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- HONDA Shuta
- Department of Oral Pathology,
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- TOMINAGA Kazuya
- Department of Oral Pathology,
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- NARUSE Kaori
- First Department of Oral and Maxillofacial Surgery,
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- MORITA Shosuke
- First Department of Oral and Maxillofacial Surgery,
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- IMAI Koichi
- Department of Biomaterials,
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- MASUNO Kazuya
- Department of Innovations in Dental Education,
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- ONO Yoshiaki
- Department of Geriatric Dentistry,
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- NISHIKAWA Tetsunari
- Department of Innovations in Dental Education,
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- TANAKA Akio
- Department of Pathology, Osaka Dental University, Osaka, Japan
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<p>In regenerative dental therapy, the development of bone scaffold materials to enable augmentation of bone for dental implant and prosthesis treatment is important. Montipora digitata exoskeleton-derived aragonite particles are porous, bioresorbable bone scaffold and applied to bone defects as natural materials. In this bone scaffold material, it is necessary to form collagen fibers which are the extracellular matrix of particles derived from Montipora digitata skeleton capillary vessels and newly formed bone. Therefore, we cultured fibroblast cells and added the particles in order to investigate the effect of cell proliferation ability and production of collagen fibers. In this study, it was observed that cultured fibroblasts were enhanced cell proliferation and collagen fiber production by adding aragonite particles.</p>
収録刊行物
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- Journal of Oral Tissue Engineering
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Journal of Oral Tissue Engineering 15 (1), 41-48, 2017
日本再生歯科医学会
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詳細情報 詳細情報について
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- CRID
- 1390001205225922816
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- NII論文ID
- 130006394590
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- ISSN
- 18800823
- 13489623
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可
