A Favorable Response to Levetiracetam in a Patient with Metastatic Adenoid Cystic Carcinoma
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- Sakata Shinya
- Department of Respiratory Medicine, Kumamoto University Hospital, Japan
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- Saeki Sho
- Department of Respiratory Medicine, Kumamoto University Hospital, Japan
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- Terasaki Yasuhiro
- Department of Analytic Human Pathology, Nippon Medical School, Japan
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- Natori Yoshihiro
- Department of Neurosurgery, Iizuka Hospital, Japan
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- Fujii Kazuhiko
- Department of Respiratory Medicine, Kumamoto University Hospital, Japan
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抄録
<p>Adenoid cystic carcinoma (ACC) is a rare cancer, and there are no standard-of-care treatments for patients with metastatic ACC. We herein report a patient with lung metastasis of ACC who achieved a favorable response to levetiracetam. A 52-year-old Japanese man was admitted to our hospital because of multiple lung metastases of ACC. We performed first-line chemotherapy with cisplatin plus gemcitabine, and subsequently oral S-1 as second-line chemotherapy, which resulted in disease progression. The patient developed symptomatic epilepsy and received levetiracetam (250 mg twice daily). At five months after the initiation of levetiracetam, chest computed tomography showed regression of the metastatic lung lesions. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 57 (5), 721-724, 2018
一般社団法人 日本内科学会