Strategy for Construction of Anisotropic Bone Matrix by Using Biomedical Materials

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  • MATSUGAKI Aira
    Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University
  • NAKANO Takayoshi
    Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University

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  • 医用材料による細胞制御に基づく骨配向化誘導
  • イヨウ ザイリョウ ニ ヨル サイボウ セイギョ ニ モトズク ホネハイコウカ ユウドウ

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Abstract

Ordered structures in constituent materials govern their functions, sometimes much more than their amount would suggest. The crystallographic texture of apatite with a hexagonal lattice structure dominates the mechanical properties of bone more than bone mass. However, obtaining an appropriate anisotropic microstructure during the bone regeneration process remains a big challenge. A powerful strategy for the control of structural development of newly formed bone is required in bone tissue engineering, in order to realize functional bone tissue regeneration. We developed essential strategies for control of bone matrix anisotropy by using biomedical materials involving polymeric, metallic and other related materials.

Journal

  • KOBUNSHI RONBUNSHU

    KOBUNSHI RONBUNSHU 75 (2), 164-173, 2018

    The Society of Polymer Science, Japan

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