Importance of Achieving a "Fit" Cardiorespiratory Fitness Level for Several Years on the Incidence of Type 2 Diabetes Mellitus: A Japanese Cohort Study

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Author(s)

    • Momma Haruki
    • Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering|Department of Health Promotion and Exercise, National Institutes of Biomedical Innovation, Health and Nutrition
    • Huang Cong
    • Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering
    • Nagatomi Ryoichi
    • Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering
    • Blair Steven N.
    • Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina|Department of Exercise Science, Arnold School of Public Health, University of South Carolina
    • Sawada Susumu S.
    • Department of Health Promotion and Exercise, National Institutes of Biomedical Innovation, Health and Nutrition
    • Sloan Robert A.
    • Department of Psychosomatic Internal Medicine, Graduate Medical and Dental School, Kagoshima University
    • Gando Yuko
    • Department of Health Promotion and Exercise, National Institutes of Biomedical Innovation, Health and Nutrition
    • Terada Shin
    • Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo
    • Miyachi Motohiko
    • Department of Health Promotion and Exercise, National Institutes of Biomedical Innovation, Health and Nutrition

Abstract

<p><b>Background:</b> The "Physical Activity Reference for Health Promotion 2013" provides "fit" reference values for cardiorespiratory fitness (CRF) for good health. The importance of achieving a fit CRF level for several years on the subsequent prevention of type 2 diabetes mellitus (T2DM) remains to be clarified.</p><p><b>Methods:</b> This cohort study was conducted in 2,235 nondiabetic males aged 21 to 59 years, enrolled in April 1986 through March 1987. We calculated the ratio of the area under the curve (AUC<sub>ratio</sub>) for actual measured values and the AUC for the reference values of CRF in each individual during an 8-year measurement period before the baseline. According to whether they met a fit CRF level or not, participants were categorized into groups based on the AUC<sub>ratio</sub> (Fit<sub>AUC</sub> or Unfit<sub>AUC</sub>) and initial CRF (Fit<sub>initial</sub> or Unfit<sub>initial</sub>), respectively. T2DM was evaluated on health checkups until March 2010.</p><p><b>Results:</b> During the follow-up period, 400 men developed T2DM. After adjustment for confounders, as compared with those in the Fit<sub>AUC</sub> group, the hazard ratio (HR) for those in the Unfit<sub>AUC</sub> group was 1.33 (95% confidence interval [CI], 1.06–1.65). A combined analysis with the categories of initial value and AUC<sub>ratio</sub> showed that, compared with the Fit<sub>initial</sub> and Fit<sub>AUC</sub> group, the HRs of Fit<sub>initial</sub> and Unfit<sub>AUC</sub>, Unfit<sub>initial</sub> and Fit<sub>AUC</sub>, and Unfit<sub>initial</sub> and Unfit<sub>AUC</sub> groups were 1.41 (95% CI, 0.99–2.00), 1.18 (95% CI, 0.81–1.70), and 1.40 (95% CI, 1.08–1.83), respectively.</p><p><b>Conclusion:</b> Achievement of a fit CRF level established in the Japan physical activity guideline for several years was associated with lower subsequent risk of T2DM.</p>

Journal

  • Journal of Epidemiology

    Journal of Epidemiology 28(5), 230-236, 2018

    Japan Epidemiological Association

Codes

  • NII Article ID (NAID)
    130006732083
  • Text Lang
    ENG
  • ISSN
    0917-5040
  • Data Source
    J-STAGE 
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