Comparison of the Brachial-ankle Pulse Wave Velocity between Patients with Acute Coronary Syndrome and Effort Angina Pectoris

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  • Yamasa Toshihiko
    Department of Cardiology, Nagasaki Rosai Hospital, Japan
  • Ikeda Satoshi
    Division of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Koga Seiji
    Division of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Kawano Hiroaki
    Division of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Kaibara Shuuhei
    Department of Cardiology, Nagasaki Rosai Hospital, Japan
  • Maemura Koji
    Division of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan

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<p>Objective Coronary artery disease (CAD) is one of the clinical categories of atherosclerotic diseases. There have been reports indicating that the pathological findings of coronary artery plaque differ between acute coronary syndrome (ACS) and effort angina pectoris (EAP). The brachial-ankle pulse wave velocity (baPWV) has been reported to be a good indicator of atherosclerotic disease. However, the baPWV may not be equally effective for evaluating ACS and EAP. In this study, we compared the baPWV in patients with ACS and those with EAP. </p><p>Methods Two hundred and seventy patients were enrolled in this study. All patients underwent coronary angiography, and were separated into normal (CONT), ACS and EAP groups according to the clinical and coronary angiographic findings. The baPWV was evaluated and the results were compared among the groups. </p><p>Results The baPWV was significantly higher in the EAP group than in the other groups. The baPWV in the ACS group was almost the same as that of the CONT group and was significantly higher in the EAP group than in the ACS group across almost all age groups. </p><p>Conclusion The present study showed that the baPWV is high in patients with EAP. In contrast, the baPWV in the ACS group was almost normal and was similar to that of the CONT group. ACS occurs due to plaque rupture induced by atherosis, which may occur independent of sclerosis in the coronary artery. EAP may occur in proportion to systemic arterial sclerosis. The baPWV is suitable for screening for EAP, but not for ACS. </p>

収録刊行物

  • Internal Medicine

    Internal Medicine 57 (10), 1371-1374, 2018-05-15

    一般社団法人 日本内科学会

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