Efficient Flow Fischer Esterification of Carboxylic Acids with Alcohols Using Sulfonic Acid-Functionalized Silica as Supported Catalyst

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Author(s)

Abstract

<p>Flow Fischer esterification of carboxylic acids using hydroxy-substituted sulfonic acid-functionalized silica (HO-SAS) packed into a stainless steel column reactor was investigated. HO-SAS well catalyzed flow esterification of long chain carboxylic acids with methanol within 3 min of residence time at 110 °C, and the methyl esters were quantitatively obtained. The flow esterification protocol was applied to the synthesis of a variety of esters (19 examples) and scalable synthesis was also successful.</p>

Journal

  • Bulletin of the Chemical Society of Japan

    Bulletin of the Chemical Society of Japan 90(5), 607-612, 2017

    The Chemical Society of Japan

Codes

  • NII Article ID (NAID)
    130006770707
  • NII NACSIS-CAT ID (NCID)
    AA00580132
  • Text Lang
    ENG
  • ISSN
    0009-2673
  • NDL Article ID
    028167385
  • NDL Call No.
    Z53-B35
  • Data Source
    NDL  J-STAGE 
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