Molecular investigations of development and diseases of the brain of higher mammals using the ferret Molecular investigations of development and diseases of the brain of higher mammals using the ferret

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Author(s)

    • KAWASAKI Hiroshi KAWASAKI Hiroshi
    • Department of Medical Neuroscience, Graduate School of Medical Sciences, Kanazawa University|Brain/Liver Interface Medicine Research Center, Kanazawa University

Abstract

<p>The brains of higher mammals such as primates and carnivores contain well-developed unique brain structures. Uncovering the physiological functions, developmental mechanisms and evolution of these brain structures would greatly facilitate our understanding of the human brain and its diseases. Although the anatomical and electrophysiological features of these brain structures have been intensively investigated, our knowledge about their molecular bases is still limited. To overcome this limitation, genetic techniques for the brains of carnivores and primates have been established, and molecules whose expression patterns correspond to these brain structures were identified recently. To investigate the functional roles of these molecules, rapid and efficient genetic manipulation methods for higher mammals have been explored. In this review, recent advances in molecular investigations of the brains of higher mammals are discussed, mainly focusing on ferrets (<i>Mustela putorius furo</i>).</p>

Journal

  • Proceedings of the Japan Academy, Series B

    Proceedings of the Japan Academy, Series B 93(5), 259-269, 2017

    The Japan Academy

Codes

  • NII Article ID (NAID)
    130006770759
  • NII NACSIS-CAT ID (NCID)
    AA00785485
  • Text Lang
    ENG
  • Article Type
    journal article
  • ISSN
    0386-2208
  • NDL Article ID
    028203262
  • NDL Call No.
    Z53-T495
  • Data Source
    NDL  IR  J-STAGE 
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