Scaling relationship between intra-nuclear DNA density and chromosomal condensation in metazoan and plant

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Author(s)

Abstract

<p>Across species, eukaryotic chromosomes share common features at the molecular level. However, common features at the cellular level are not well investigated. A correlation has been suggested between the linear packing ratio of mitotic chromosomes and the intra-nuclear DNA density, by comparing these values in the nematode <i>Caenorhabditis elegans</i>. In this study, these values were measured and compared among several metazoan and plant species. The obtained values corroborated the correlation proposed in the previous study, supporting the theory that intra-nuclear DNA density is a common regulator of chromosome condensation. Moreover, the comparison among different species suggested a correlation between the length of a mitotic chromosome and the nuclear volume to the power of 2/3. Given this observation, we speculate that: (i) a rate-limiting component defines the length of a mitotic chromosome that is proportional to the nuclear surface area, and (ii) such regulation of the mitotic chromosomal length may play a role in maintaining the ratio between the cell size and the metaphase plate.</p>

Journal

  • Chromosome Science

    Chromosome Science 19(1-4), 43-49, 2016

    THE SOCIETY OF CHROMOSOME RESEARCH

Codes

  • NII Article ID (NAID)
    130006837152
  • NII NACSIS-CAT ID (NCID)
    AA11163057
  • Text Lang
    ENG
  • ISSN
    1344-1051
  • NDL Article ID
    028154712
  • NDL Call No.
    Z54-J215
  • Data Source
    NDL  J-STAGE 
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