Biological response of Octacalcium Phosphate Combined with collagen implanted in subperiosteal region

• 鈴木 祐子

  東北大院・歯・口腔システム補綴学分野

• 鎌倉 慎治

  東北大院・医・細胞治療開発分野

• 羽鳥 弘毅

  東北大院・歯・口腔システム補綴学分野

• 佐々木 和夫

  日本ハム株式会社

• 本田 義知

  東北大院・歯・顎口腔機能創建学分野

• 穴田 貴久

  東北大院・歯・顎口腔機能創建学分野

• 佐々木 啓一

  東北大院・歯・口腔システム補綴学分野

• 鈴木 治

  東北大院・歯・顎口腔機能創建学分野

抄録

Previous studies showed that octacalcium phosphate (OCP) combined with collagen (OCP/Col) enhances bone regeneration in bone defect. In the present study, OCP/Col disc (1 mm or 3 mm in thickness) were implanted into the periosteal region in rat crania to investigate the bone regenerative properties of OCP/Col. The maximum thickness of the bone with implant was measured parallel to the calvaria. The histological sections were cut and activities of tartrate resistant acid phosphatase (TRAP) were stained to examine phagocytotic multinucleated giant cells. The effect of implantation on crystalline phase of OCP in the implant was examined by X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). The present study suggests that new bone formation on OCP/Col and biodegradation of OCP/Col are depending on the thickness of OCP/Col.

収録刊行物

• 日本歯科理工学会学術講演会要旨集

  日本歯科理工学会学術講演会要旨集 2007f (0), 39-39, 2007

  日本歯科理工学会

キーワード

• octacalcium phosphate
• bone regeneration
• biodegradation

詳細情報

• CRID: 1390282680571518848
• NII論文ID: 130006961923
• DOI: 10.14832/gsjsdmd.2007f.0.39.0
• 本文言語コード: en
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可