新規エーテル系溶剤シクロペンチルメチルエーテル(CPME)の開発

• 渡辺 澄

  日本ゼオン_(株)_

• 小越　 直人

  日本ゼオン_(株)_

• 三木　 英了

書誌事項

タイトル別名

• Development of A New Solvent Cyclopentyl Methyl Ether(CPME)

抄録

Cyclopentyl methyl ether (CPME) has become available in a commercial quantity since Nov. 2005 from Zeon Corporation. High boiling point as well as preferable characters (low formation of peroxides, relative stability under acidic or basic conditions, formation of azeotropes with water, a low affinity for water and small evaporation energy compared to other ethers coupled with narrow explosion range) make CPME as an affordable and alternative solvent with future prosperity. It is useful for general organometallic reactions including Grignard reactions, enolate formation, Claisen condensation, reductions and Pd-based transformations such as Buchwald-Hartwig amination. Consequently, it is safe to conclude that CPME is emerging as a potential alternative for THF, dioxane and DME. Due to these unique properties and applications, CPME possesses particular advantages and renders some conventional reaction sequences in one pot or easier process as a result of solvent unification.

収録刊行物

• 反応と合成の進歩シンポジウム 発表要旨概要

  反応と合成の進歩シンポジウム 発表要旨概要 32 (0), 88-88, 2006

  日本薬学会化学系薬学部会

キーワード

• CPME
• peroxide
• Zeon

詳細情報

• CRID: 1390001205633779200
• NII論文ID: 130006995930
• DOI: 10.14895/hannou.32.0.88.0
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可