Spontaneous Reduction in Abnormal Myocardial Uptake of Fluorine-18 Fluorodeoxygluose in a Patient with Cardiac Sarcoidosis

• Terasaki Fumio

  Medical Education Center, Osaka Medical College Department of Cardiology, Osaka Medical College

• Fujita Shu-ichi

  Department of Cardiology, Osaka Medical College

• Kanzaki Yumiko

  Department of Cardiology, Osaka Medical College

• Hirose Yoshinobu

  Department of Pathology, Osaka Medical College

• Ishizaka Nobukazu

  Department of Cardiology, Osaka Medical College

Abstract

Fluorine-18 fluorodeoxygluose (¹⁸F-FDG) positron emission tomography (PET) is a useful tool for evaluating disease activity in sarcoidosis including cardiac involvement. A 67-year-old patient who developed atrioventricular block requiring permanent pacemaker implantation was diagnosed with cardiac sarcoidosis. The patient did not undergo steroid or immunosuppressive therapy but underwent serial ¹⁸F-FDG PET examination, which showed spontaneous reduction in the myocardial FDG uptake, indicating the remission of immune-inflammatory activity. Although the global systolic function remained preserved, thinning of the septal wall emerged during the clinical course of follow-up, which is characteristic for cardiac sarcoidosis.

Journal

• International Heart Journal

  International Heart Journal 59 (3), 647-651, 2018-05-31

  International Heart Journal Association

Keywords

• Natural history
• Prognosis
• Diagnostic imaging
• Disease activity

Details

• CRID: 1390282763013317248
• NII Article ID: 130007378352
• DOI: 10.1536/ihj.17-315
• ISSN: 13493299
• ISSN: 13492365
• PubMed: 29681578
• Web Site: https://www.jstage.jst.go.jp/article/ihj/59/3/59_17-315/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2019070443
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed