Spatial Restriction within Intracranial Epidermoid Cysts Observed Using Short Diffusion-time Diffusion-weighted Imaging

  • Andica Christina
    Department of Radiology, Juntendo University Graduate School of Medicine
  • Hori Masaaki
    Department of Radiology, Juntendo University Graduate School of Medicine
  • Kamiya Kouhei
    Department of Radiology, Graduate School of Medicine, The University of Tokyo
  • Koshino Saori
    Department of Radiology, Juntendo University Graduate School of Medicine Department of Radiology, Graduate School of Medicine, The University of Tokyo
  • Hagiwara Akifumi
    Department of Radiology, Juntendo University Graduate School of Medicine Department of Radiology, Graduate School of Medicine, The University of Tokyo
  • Kamagata Koji
    Department of Radiology, Juntendo University Graduate School of Medicine
  • Fukunaga Issei
    Department of Radiology, Juntendo University Graduate School of Medicine
  • Hamasaki Nozomi
    Department of Radiology, Juntendo University Graduate School of Medicine
  • Suzuki Michimasa
    Department of Radiology, Juntendo University Graduate School of Medicine
  • Feiweier Thorsten
    Siemens Healthcare GmbH
  • Murata Katsutoshi
    Siemens Healthcare Japan KK
  • Arakawa Atsushi
    Department of Human Pathology, Juntendo University School of Medicine
  • Kondo Akihide
    Department of Neurosurgery, Juntendo University School of Medicine
  • Akiyama Osamu
    Department of Neurosurgery, Juntendo University School of Medicine
  • Aoki Shigeki
    Department of Radiology, Juntendo University Graduate School of Medicine

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<p>We report two cases of pathologically proven intracranial epidermoid cysts. Both cases were scanned with diffusion-weighted imaging using pulsed gradient spin-echo (PGSE) and oscillating gradient spin-echo (OGSE; 50 Hz) prototype sequences with diffusion times of 47.3 ms and 8.5 ms, respectively. The apparent diffusion coefficient measured by OGSE was higher than that measured by PGSE, indicating the spatial restriction of water diffusion in the laminated keratin layers within the cyst as demonstrated by histopathology.</p>

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