Paraneoplastic Pemphigus Associated with B-cell Chronic Lymphocytic Leukemia Treated with Ibrutinib and Rituximab
-
- Ito Yuta
- Department of Hematology, National Cancer Center Hospital, Japan
-
- Makita Shinichi
- Department of Hematology, National Cancer Center Hospital, Japan
-
- Maeshima Akiko Miyagi
- Department of Pathology, National Cancer Center Hospital, Japan
-
- Hatta Shunsuke
- Department of Hematology, National Cancer Center Hospital, Japan
-
- Suzuki Tomotaka
- Department of Hematology, National Cancer Center Hospital, Japan
-
- Yuda Sayako
- Department of Hematology, National Cancer Center Hospital, Japan
-
- Fukuhara Suguru
- Department of Hematology, National Cancer Center Hospital, Japan
-
- Munakata Wataru
- Department of Hematology, National Cancer Center Hospital, Japan Rare Cancer Center, National Cancer Center Hospital, Japan
-
- Suzuki Tatsuya
- Department of Hematology, National Cancer Center Hospital, Japan
-
- Maruyama Dai
- Department of Hematology, National Cancer Center Hospital, Japan
-
- Izutsu Koji
- Department of Hematology, National Cancer Center Hospital, Japan
この論文をさがす
抄録
<p>Paraneoplastic pemphigus (PNP) is a severe autoimmune blistering disease associated with an underlying malignancy, and its prognosis is poor. We herein report the first patient with B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (B-CLL/SLL)-associated PNP successfully treated with the Bruton's tyrosine kinase inhibitor ibrutinib and rituximab. Although his PNP lesions did not improve with ibrutinib monotherapy, the combination of ibrutinib and rituximab was effective against B-CLL/SLL-associated PNP. This case suggests that ibrutinib plus rituximab may be a potent therapeutic option for B-CLL/SLL-associated PNP that is hard to control with ibrutinib alone. </p>
収録刊行物
-
- Internal Medicine
-
Internal Medicine 57 (16), 2395-2398, 2018-08-15
一般社団法人 日本内科学会
- Tweet
詳細情報
-
- CRID
- 1390282763033177472
-
- NII論文ID
- 130007434748
-
- ISSN
- 13497235
- 09182918
-
- PubMed
- 29526963
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可