Outbreak of Tuberculosis in Cynomolgus Monkeys (<i>Macaca fascicularis</i>) Imported to Japan

• OE Saki

  Animal Quarantine Service, Narita Branch, Ministry of Agriculture, Forestry and Fisheries

• OKAMURA Naomi

  Animal Quarantine Service, Narita Branch, Ministry of Agriculture, Forestry and Fisheries

• AKUZAWA Yoshinori

  Animal Quarantine Service, Narita Branch, Ministry of Agriculture, Forestry and Fisheries

• CHIKAMATSU Kinuyo

  Department of Mycobacterium Reference and Research, the Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association

• YAMADA Hiroyuki

  Department of Mycobacterium Reference and Research, the Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association

• MURASE Yoshiro

  Department of Mycobacterium Reference and Research, the Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association

• MITARAI Satoshi

  Department of Mycobacterium Reference and Research, the Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association

Bibliographic Information

Other Title

• 輸入カニクイザルにおける結核症の集団発生事例
• ユニュウ カニクイザル ニ オケル ケッカクショウ ノ シュウダン ハッセイ ジレイ

Abstract

Thirty-two cynomolgus monkeys (Macaca fascicularis) under import quarantine at the Animal Quarantine Service in Japan were examined for tuberculosis by tuberculin skin test. Nine of the 32 showed positive and/or suspicious reactions. Although they had no apparent symptoms suggestive of tuberculosis, pulmonary multifocal nodular lesions were present with acid-fast positive bacilli on some tissue samples, such as the lungs and lymph nodes. Mycobacterium tuberculosis was isolated from some tissue samples. The results of the tuberculin skin test and histopathological findings indicated that Mycobacterium tuberculosis might have infected some monkeys more than a few months prior to the test, and expanded in the same colony. The genotype of the isolated Mycobacterium tuberculosis was determined as EAI2_MANILLA by spoligotyping.

Journal

• Journal of the Japan Veterinary Medical Association

  Journal of the Japan Veterinary Medical Association 71 (7), 369-375, 2018-07-20

  Japan Veterinary Medical Association

Keywords

• cynomolgus monkeys
• EAI2_MANILLA
• import quarantine
• tuberculosis

Details

• CRID: 1390845712986566528
• NII Article ID: 130007437356
• NII Book ID: AN00191857
• DOI: 10.12935/jvma.71.369
• ISSN: 21860211
• ISSN: 04466454
• NDL BIB ID: 029133373
• Web Site: https://agriknowledge.affrc.go.jp/RN/2030922595
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I029133373
• Web Site: https://www.jstage.jst.go.jp/article/jvma/71/7/71_369/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2018286678
• Text Lang: ja
• Data Source:
  • JaLC
  • IRDB
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed