Contrast-enhanced Ultrasonography Preceded by Partial Mastectomy to Estimate the Spread of Breast Cancer

• MAKITA Masujiro

  Department of Breast Surgery, Nippon Medical School Musashikosugi Hospital

• AKASU Haruki

  Department of Endocrine Surgery, Nippon Medical School Musashikosugi Hospital

• JIKUZONO Tomoo

  Kanaji Hospital, Department of Endocrine Surgery, Nippon Medical School Hospital

• ICHIKAWA Taro

  Department of Diagnostic Radiology, Nippon Medical School Musashikosugi Hospital

• GOMI Naoya

  Department of Diagnostic Radiology, Cancer Institute Hospital

• KIKUCHI Mari

  Department of Diagnostic Radiology, National Cancer Center Hospital

• MOTODA Norio

  Department of Pathology, Nippon Medical School Musashikosugi Hospital

• KITAYAMA Yasuhiko

  Department of Pathology, Nippon Medical School Musashikosugi Hospital

Bibliographic Information

Other Title

• 造影超音波による乳癌の広がり診断
• ゾウエイ チョウオンパ ニ ヨル ニュウガン ノ ヒロガリ シンダン

Abstract

The aim of this study was to compare the use of magnetic resonance imaging (MRI) and contrast-enhanced ultrasonography (CEUS) in the evaluation of the spread of breast cancer by pathological assessment of specimens that were resected immediately after CEUS. We enrolled 21 patients who provided written informed consent and underwent partial mastectomy for breast cancer between September 2015 and June 2016. Three distances of cancer spreading, based on MRI (d-MRI), CEUS (d-CEUS), and specimen (d-PAT) evaluations, were measured in each patient, and the rate of correspondence between d-MRI and d-PAT was compared with that between d-CEUS and d-PAT. CEUS preceded by partial mastectomy under general anesthesia, and the spread of breast cancer was assessed by enhancement of a low echoic spot. Partial mastectomy was performed according to the spreading revealed by CEUS, and the resected specimen was serially sectioned and evaluated. The rate of correspondence between d-MRI and d-PAT was 57.1%, and that between d-CEUS and d-PAT was 54.2%. Both d-MRI and d-CEUS were correlated with d-PAT (r=0.755, p<0.0001), and d-CEUS was also correlated with d-MRI. CEUS was as useful as MRI for the estimation of the spread of breast cancer. Because the patients were in the supine position during CEUS, similar to the position assumed during surgery, CEUS was also useful in decision-making regarding the resection line for breast-conserving surgery.

Journal

• Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)

  Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 79 (3), 459-466, 2018

  Japan Surgical Association

Keywords

• breast cancer
• breast–conserving surgery
• contrast–enhanced ultrasonography
• intraductal spread

Details

• CRID: 1390282763050761216
• NII Article ID: 130007491773
• NII Book ID: AA11189709
• DOI: 10.3919/jjsa.79.459
• ISSN: 18825133
• ISSN: 13452843
• NDL BIB ID: 028973855
• Web Site: http://id.ndl.go.jp/bib/028973855
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I028973855
• Web Site: https://www.jstage.jst.go.jp/article/jjsa/79/3/79_459/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2018193234
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed