Isolation of Nabscessin C from <i>Nocardia abscessus</i> IFM 10029<sup>T</sup> and a Study on Biosynthetic Pathway for Nabscessins
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- Hara Shoko
- Graduate School of Pharmaceutical Sciences, Chiba University
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- Hara Yasumasa
- Graduate School of Pharmaceutical Sciences, Chiba University
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- Arai Midori A.
- Graduate School of Pharmaceutical Sciences, Chiba University
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- Kusuya Yoko
- Medical Mycology Research Center, Chiba University
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- Takahashi Hiroki
- Medical Mycology Research Center, Chiba University
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- Yaguchi Takashi
- Medical Mycology Research Center, Chiba University
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- Ishibashi Masami
- Graduate School of Pharmaceutical Sciences, Chiba University
Bibliographic Information
- Other Title
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- Isolation of Nabscessin C from Nocardia abscessus IFM 10029T and a Study on Biosynthetic Pathway for Nabscessins
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Abstract
<p>A new aminocyclitol derivative, designated nabscessin C (1), was isolated from Nocardia abscessus IFM 10029T. Nabcessin C is an isomer of nabscessins A (2) and B (3) with different positioning of the acyl group. Absolute configuration of nabscessin A was determined by conversion into the 2-deoxy-scyllo-inosamine pentaacetyl derivative (4) by hydrolysis and acetylation of 2. The biosynthetic pathway of nabscessins is proposed based on gene expression analysis.</p>
Journal
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- Chemical and Pharmaceutical Bulletin
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Chemical and Pharmaceutical Bulletin 66 (10), 976-982, 2018-10-01
The Pharmaceutical Society of Japan
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Details 詳細情報について
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- CRID
- 1390001288072747392
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- NII Article ID
- 130007492854
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- NII Book ID
- AA00602100
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- ISSN
- 13475223
- 00092363
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- NDL BIB ID
- 029238172
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- PubMed
- 30270243
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed
