Manifestation of intraoperative anaphylactic shock along with latex allergy:a pediatric case report

• Sugimoto Mayumi

  Department of Pediatrics, Tokushima University

• Ono Akemi

  Department of Pediatrics, Tokushima University

• Yada Keigo

  Department of Pediatric Surgery and Pediatric Endoscopic Surgery, Tokushima University

• Mori Hiroki

  Department of Pediatric Surgery and Pediatric Endoscopic Surgery, Tokushima University

• Ishibashi Hiroki

  Department of Pediatric Surgery and Pediatric Endoscopic Surgery, Tokushima University

• Niki Noriko

  Department of Anesthesiology, Tokushima University

• Kagami Shoji

  Department of Pediatrics, Tokushima University

Abstract

Natural rubber latex (NRL) allergy is one of the most important causes of severe anaphylaxis during medical intervention. We report a pediatric case of latex allergy with multiple surgical histories. A 12‐year‐old girl developed anaphylactic shock during the pyeloplasty for ureteropelvic junction restenosis. Latex gloves or medications used during the surgery were suspected to be the cause of anaphylactic shock. We diagnosed her latex allergy on the basis of the results that serum latex‐specific IgE, skin prick tests of extract from NRL gloves and recombinant Hev b 6.02 solution were positive. Basophil activation test of NRL gloves was also positive, supporting the diagnosis of immediate allergic reactions caused by NRL. It was speculated that a history of multiple surgeries in infancy became a trigger of sensitization to latex in this patient. Reoperation after the diagnosis of NRL allergy was carried out in a latex‐free environment and completed without any allergic symptoms. It would be necessary to perform the pre‐screening of latex allergy to prevent the onset of latex allergy especially in the patients with multiple surgical histories. J. Med. Invest. 65:292‐295, August, 2018

Journal

• The Journal of Medical Investigation

  The Journal of Medical Investigation 65 (3.4), 292-295, 2018

  The University of Tokushima Faculty of Medicine

Keywords

• latex allergy
• anaphylaxis
• latex‐specific IgE
• skin prick test
• basophil activation test

Details

• CRID: 1390282763071551232
• NII Article ID: 130007495829
• NII Book ID: AA12022913
• DOI: 10.2152/jmi.65.292
• ISSN: 13496867
• ISSN: 13431420
• PubMed: 30282877
• Web Site: http://repo.lib.tokushima-u.ac.jp/112277
• Web Site: https://www.jstage.jst.go.jp/article/jmi/65/3.4/65_292/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2020012963
• Text Lang: en
• Data Source:
  • JaLC
  • IRDB
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed