Factors associated with treatment satisfaction in patients with type 2 diabetes mellitus using oral glucose-lowering agents: a cross-sectional study in urban districts in Japan
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- Hayashi Isao
- Hayashi Clinic, Nishinomiya, Hyogo, Japan
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- Watanabe Nobuaki
- Watanabe Clinic, Nishinomiya, Hyogo, Japan
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- Nakata Shinsuke
- Nakata Clinic, Kaizuka, Osaka, Japan
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- Komatsu Ryoya
- Ryoya Komatsu Clinic, Izumisano, Osaka, Japan
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- Motoda Saori
- Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan
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- Fujita Yukari
- Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan
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- Ishibashi Chisaki
- Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan
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- Yamaguchi Baden Megu
- Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan
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- Kimura Takekazu
- Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan
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- Takahara Mitsuyoshi
- Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan Department of Diabetes Care Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan
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- Kozawa Junji
- Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan
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- Imagawa Akihisa
- Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan
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- Iwahashi Hiromi
- Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan Department of Diabetes Care Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan
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- Shimomura Iichiro
- Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan
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Abstract
<p>Various oral glucose-lowering agents are available in Japan. Although the objective characteristics of these drugs are well described, little is known about treatment satisfaction by patients using these agents. The aim of this study was to assess treatment satisfaction of diabetic patients visiting diabetes clinics using the Diabetes Treatment Satisfaction Questionnaire (DTSQ) and to determine the association of the DTSQ scores with various factors including oral glucose-lowering agents. The study subjects were 754 outpatients who had been treated with one or more oral glucose-lowering agents, but not insulin or glucagon-like peptide-1 receptor agonist. The collected data included the response to DTSQ as completed by the patients, various parameters pertaining diabetes treatment including adherence, motivation, life style, social support, complications and cost burden from the patients and attending physicians. The associations among satisfaction scores and various parameters were analyzed by multiple linear regression analysis. In all subjects, use of sodium-glucose cotransporter 2 inhibitor (SGLT2i) were positively, and irregular diet time were negatively associated with satisfaction scores significantly as well as some factors which had been previously reported to be associated. Subgroup analysis showed that adherence to diet and use of SGLT2i were positively in obese (body mass index ≥25 kg/m2), and HbA1c and irregular work time were negatively in non-obese (<25 kg/m2) patients associated with satisfaction scores. These results suggest that SGLT2i is really used with high satisfaction, especially by obese patients and that factors associated with treatment satisfaction might differ between obese and non-obese patients using oral glucose-lowering agents.</p>
Journal
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- Endocrine Journal
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Endocrine Journal 65 (10), 1001-1009, 2018
The Japan Endocrine Society
