Dysembryoplastic Neuroepithelial Tumor with Extension to the Basal Cistern: A Case Report

• Ohnaka Keisuke

  Department of Neurosurgery, Tokyo Medical and Dental University

• Shimizu Kazuhide

  Department of Neurosurgery, Tokyo Medical and Dental University

• Kobayashi Daisuke

  Department of Human Pathology, Tokyo Medical and Dental University

• Inaji Motoki

  Department of Neurosurgery, Tokyo Medical and Dental University

• Maehara Taketoshi

  Department of Neurosurgery, Tokyo Medical and Dental University

Abstract

Dysembryoplastic neuroepithelial tumor (DNET) is a benign tumor that causes intractable epilepsy at young ages. In this report, we present a rare case of a 28-year-old female with a DNET in the temporal lobe showing extracortical extension to the basal cistern. Enlarging contrast enhancement on MRI, a trait unusual for a benign tumor, suggested the possibility of a malignant glioma. An intraoperative rapid pathological diagnosis of a low-grade glioma in conjunction with electrocorticographic findings supported a surgical strategy of tumor resection alone with preservation of the hippocampus. For this type of DNET with uncommon extension and MRI features, a combination of electro-physiological and morphological analyses based on preoperative studies for epileptogenic focus detection is key to achieving good seizure control and tumor removal with preservation of the patient's memory function.

Journal

• Epilepsy & Seizure

  Epilepsy & Seizure 10 (1), 87-94, 2018

  JAPAN EPILEPSY SOCIETY

Keywords

• Dysembryoplastic neuroepithelial tumor
• Extracortical extension
• Temporal lobe epilepsy
• Brain tumor

Details

• CRID: 1390001288089680256
• NII Article ID: 130007510363
• DOI: 10.3805/eands.10.87
• ISSN: 18825567
• Web Site: https://www.jstage.jst.go.jp/article/eands/10/1/10_87/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2020203751
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed