Neutrons in Biological Research

• Kataoka Mikio

  Graduate School of Materials Science, Nara Institute of Science and Technology

Bibliographic Information

Other Title

• 生物研究における中性子
• 中性子生物(1)生物研究における中性子
• チュウセイシ セイブツ(1)セイブツ ケンキュウ ニ オケル チュウセイシ

Abstract

Neutrons can see hydrogen (deuterium) atom structurally and dynamically. The specific feature makes neutrons unique method for biological science. Neutron protein crystallography enables to identify hydrogen atom positions, which leads to the understanding of hydrogen bond network around the active site. One successful example is the discovery of the low barrier hydrogen bond in photoactive yellow protein. Recent advances in incoherent scattering enable to distinguish hydration water dynamics from protein dynamics. The construction of neutron dynamic data base is now discussing. Although criticism against the usefulness of neutrons in biology has been raised, we should be confident that neutron can contribute to the progress of biological science substantially.

Journal

• hamon

  hamon 21 (4), 243-246, 2011

  The Japanese Society for Neutron Science

Keywords

• incoherent scattering
• crystallography
• protein dynamics
• hydrogen bond
• hydration water

Details

• CRID: 1390001288092236416
• NII Article ID: 130007516830
• NII Book ID: AA11905115
• DOI: 10.5611/hamon.21.4_243
• ISSN: 1884636X
• ISSN: 1349046X
• NDL BIB ID: 023432029
• Web Site: http://id.ndl.go.jp/bib/023432029
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I023432029
• Web Site: https://www.jstage.jst.go.jp/article/hamon/21/4/21_243/_pdf
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed