Common Effects of Incorporated <i>n</i>-Alkane Derivatives on Molecular Packing and Phase Behavior of DPPC Bilayers

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Author(s)

    • Usuda Hatsuho
    • Department of Chemistry, Faculty of Pure and Applied Sciences, University of Tsukuba
    • Hishida Mafumi
    • Department of Chemistry, Faculty of Pure and Applied Sciences, University of Tsukuba
    • Yamamura Yasuhisa
    • Department of Chemistry, Faculty of Pure and Applied Sciences, University of Tsukuba
    • Saito Kazuya
    • Department of Chemistry, Faculty of Pure and Applied Sciences, University of Tsukuba

Abstract

<p>Effects of nine incorporated <i>n</i>-alkane derivatives on molecular packing and phase behavior of 1,2-dipalmitoyl-<i>sn</i>-glycero-3-phosphocholine (DPPC) bilayers were investigated using wide angle X-ray diffraction (WAXD) and differential scanning calorimetry (DSC). The incorporation commonly resulted in closer packing of the lipid alkyl chains in the ordered phase and shift of the thermal anomaly due to the main transition to a higher temperature. These common features suggest that effects of incorporated molecules on structure and phase behavior of DPPC bilayers can be classified by their shape.</p>

Journal

  • Chemistry Letters

    Chemistry Letters 47(12), 1512-1514, 2018

    The Chemical Society of Japan

Codes

  • NII Article ID (NAID)
    130007534813
  • Text Lang
    ENG
  • ISSN
    0366-7022
  • Data Source
    J-STAGE 
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