Hypoglycemia Unawareness in Insulinoma Revealed with Flash Glucose Monitoring Systems
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- Sugawa Taku
- Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan
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- Murakami Takaaki
- Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan
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- Yabe Daisuke
- Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan
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- Kashima Riko
- Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan
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- Tatsumi Makiko
- Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan
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- Ooshima Shinobu
- Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan
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- Joo Erina
- Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan
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- Wada Keiko
- Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan
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- Yoshizawa Atsushi
- Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kyoto University Graduate School of Medicine, Japan
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- Masui Toshihiko
- Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kyoto University Graduate School of Medicine, Japan
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- Nakamoto Yuji
- Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Japan
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- Yamauchi Yuki
- Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Japan
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- Kodama Yuzo
- Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Japan
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- Iemura Yoshiki
- Department of Diagnostic Pathology, Kyoto University Graduate School of Medicine, Japan
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- Ogura Masahito
- Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan
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- Yasoda Akihiro
- Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan
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- Inagaki Nobuya
- Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan
Abstract
<p>The delayed diagnosis of insulinoma remains a clinical issue. One of the main causes of such a delay is hypoglycemia unawareness. A 53-year-old woman fell unconscious during postprandial exercises. Flash glucose monitoring (FGM) systems revealed glucose profiles with fasting hypoglycemia, which facilitated the clinical diagnosis of insulinoma even though she was unaware of her hypoglycemia. The preoperative comparison of the blood glucose values provided by FGM with those obtained from capillary blood were consistent. Thus, FGM may have potential utility in revealing the presence of insulinoma-induced hypoglycemia. </p>
Journal
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- Internal Medicine
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Internal Medicine 57 (23), 3407-3412, 2018-12-01
The Japanese Society of Internal Medicine