Bacterial Meningitis Caused by β-lactamase Non-producing Ampicillin-resistant <i>Haemophilus influenzae</i> Type f in an Immunocompetent Woman

• Sakamoto Shinya

  Department of Infectious Diseases, Tokyo Metropolitan Bokutoh General Hospital, Japan

• Sakamoto Naoya

  Department of Infectious Diseases, Tokyo Metropolitan Bokutoh General Hospital, Japan

抄録

We report the case of a 36-year-old previously healthy woman who presented with fever and headache. Blood and cerebrospinal cultures and a bacterial analysis revealed the presence of β-lactamase non-producing ampicillin-resistant Haemophilus influenzae type f (Hif) with sequence type 124. Accordingly, the patient was diagnosed with bacterial meningitis with bacteremia caused by Hif. She had normal humoral immunity, and antibiotic therapy rapidly improved her condition. Our case indicates that serotype replacement can occur in Japan and suggests that a certain sequence type causes invasive Haemophilus influenzae disease, regardless of host immunity.

収録刊行物

• Internal Medicine

  Internal Medicine 58 (2), 307-310, 2019-01-15

  一般社団法人 日本内科学会

キーワード

• <i>Haemophilus influenzae</i> type f
• invasive <i>Haemophilus</i> disease
• bacterial meningitis
• β-lactamase non-producing ampicillin-resistant <i>Haemophilus influenzae</i>

詳細情報

• CRID: 1390282763084639232
• NII論文ID: 130007579746
• DOI: 10.2169/internalmedicine.0597-17
• ISSN: 13497235
• ISSN: 09182918
• PubMed: 30146561
• Web Site: https://www.jstage.jst.go.jp/article/internalmedicine/58/2/58_0597-17/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可