Convenient Method for the Production of Deuterium Gas Catalyzed by an Iridium Complex and Its Application to the Deuteration of Organic Compounds

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Author(s)

    • Enomoto Akane
    • Graduate School of Human and Environmental Studies, Kyoto University
    • Kajita Shunpei
    • Graduate School of Human and Environmental Studies, Kyoto University
    • Fujita Ken-ichi
    • Graduate School of Human and Environmental Studies, Kyoto University

Abstract

<p>A new protocol for the production of deuterium gas from easily-obtainable deuterated methanol and deuterium oxide has been developed. The reaction of deuterated methanol and deuterium oxide in the presence of an iridium catalyst bearing a functional bipyridonate ligand and sodium hydroxide under reflux for 48 hours gave deuterium gas in 63% yield. Deuteration reactions of unsaturated compounds and bromo-substituted aromatic compounds using the generated deuterium gas in the presence of palladium/charcoal catalyst were also investigated.</p>

Journal

  • Chemistry Letters

    Chemistry Letters 48(2), 106-109, 2019

    The Chemical Society of Japan

Codes

  • NII Article ID (NAID)
    130007590311
  • Text Lang
    ENG
  • ISSN
    0366-7022
  • Data Source
    J-STAGE 
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