Biological Safety of Mixed Acid Heat Treatment in SLM (Selective Laser Melting Technique) Titanium Mesh

DOI 被引用文献1件
  • INUI Shihoko
    Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan
  • YAMAMOTO Kayoko
    Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan
  • KATO-KOGOE Nahoko
    Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan
  • NAKAJIMA Yoichiro
    Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan
  • INOUE Kazuya
    Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan
  • NAKANO Hiroyuki
    Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan
  • YAMAGUCHI Seiji
    Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Japan
  • HIRATA Azumi
    Department of Anatomy and Cell Biology, Osaka Medical College, Osaka, Japan
  • KONDO Yoichi
    Department of Anatomy and Cell Biology, Osaka Medical College, Osaka, Japan
  • UENO Takaaki
    Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan

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<p>A titanium (Ti) mesh using the Selective Laser Melting (SLM) technique was subjected to surface modification by mixed acid heating, and it was applied to a rat calvarial bone defect model. Safety of the mixed acid heat treatment on the surface was evaluated by investigating the inflammatory response based on macroscopic and microscopic findings. Worsening of inflammatory reactions was not observed in the SLM Ti mesh-embedded group at 2, 4 or 7 weeks. These results suggest that mixed acid and heat treatment surface modification Ti mesh is safe.</p>

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