<i>De Novo</i> Vestibular Schwannoma: A Report of Three Cases

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  • Kubota Masaaki
    Department of Neurosurgery, Chiba Medical Center, Chiba, Chiba, Japan;
  • Yamakami Iwao
    Department of Neurosurgery, Chiba Medical Center, Chiba, Chiba, Japan;
  • Kubota Shunsuke
    Department of Neurosurgery, Chiba Medical Center, Chiba, Chiba, Japan;
  • Higuchi Yoshinori
    Department of Neurological Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba, Japan

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<p>The reported growth rate of vestibular schwannoma varied widely in the literature. However, emergence of vestibular schwannoma remains unsolved. We presented three patients who had undergone previous magnetic resonance imaging (MRI) confirming the absence of tumor and were diagnosed with a unilateral vestibular schwannoma with a diameter of 18–30 mm, 6–9 years after the initial MRI. One patient had solid tumor and experienced stereotactic radiosurgery. Following stereotactic radiosurgery, continuous tumor growth led to hydrocephalus and trigeminal dysfunction, resolved by surgical removal. Other two patients had the tumor with cystic component and experienced surgical removal as first treatment. All tumors were pathologically diagnosed as schwannomas without evidence of high potential of proliferation. This is the first report of three patients with de novo vestibular schwannoma, showing tumor emergence and rapid growth in a short period. Considering a de novo aspect, the “wait and scan” policy may not be appropriate for the subset of VS such as de novo VS.</p>

収録刊行物

  • NMC Case Report Journal

    NMC Case Report Journal 6 (2), 47-50, 2019

    一般社団法人 日本脳神経外科学会

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