Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the "Target Sign"
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<p>We herein report the case of a 60-year-old man with a "target sign" in the left frontal lobe on magnetic resonance imaging (MRI), which is thought to be a specific sign of cerebral toxoplasmosis. <sup>18</sup>F-fluorodeoxyglucose-positron emission tomography showed no increased uptake, and <sup>201</sup>Tl-single photon emission computed tomography showed the focal uptake in the left frontal lesion. On a brain biopsy, the patient was given a definitive diagnosis of brain metastasis from diffuse large B-cell lymphoma, and cerebral toxoplasmosis was excluded. In the present case, multilayer intensities on MRI may reflect the fast-growing nature of this tumor. </p>
- Internal Medicine
Internal Medicine 58(8), 1157-1162, 2019
The Japanese Society of Internal Medicine