Changing the Currently Held Concept of Cerebrospinal Fluid Dynamics Based on Shared Findings of Cerebrospinal Fluid Motion in the Cranial Cavity Using Various Types of Magnetic Resonance Imaging Techniques
-
- MATSUMAE Mitsunori
- Department of Neurosurgery, Tokai University School of Medicine
-
- KURODA Kagayaki
- Department of Human and Information Sciences, School of Information Science and Technology, Tokai University
-
- YATSUSHIRO Satoshi
- Department of Human and Information Sciences, School of Information Science and Technology, Tokai University BioView Inc., Tokyo, Japan;
-
- HIRAYAMA Akihiro
- Department of Neurosurgery, Tokai University School of Medicine
-
- HAYASHI Naokazu
- Department of Neurosurgery, Tokai University School of Medicine
-
- TAKIZAWA Ken
- Department of Ophthalmology, Tokai University School of Medicine
-
- ATSUMI Hideki
- Department of Neurosurgery, Tokai University School of Medicine
-
- SORIMACHI Takatoshi
- Department of Neurosurgery, Tokai University School of Medicine
この論文をさがす
抄録
<p>The “cerebrospinal fluid (CSF) circulation theory” of CSF flowing unidirectionally and circulating through the ventricles and subarachnoid space in a downward or upward fashion has been widely recognized. In this review, observations of CSF motion using different magnetic resonance imaging (MRI) techniques are described, findings that are shared among these techniques are extracted, and CSF motion, as we currently understand it based on the results from the quantitative analysis of CSF motion, is discussed, along with a discussion of slower water molecule motion in the perivascular, paravascular, and brain parenchyma. Today, a shared consensus regarding CSF motion is being formed, as follows: CSF motion is not a circulatory flow, but a combination of various directions of flow in the ventricles and subarachnoid space, and the acceleration of CSF motion differs depending on the CSF space. It is now necessary to revise the currently held concept that CSF flows unidirectionally. Currently, water molecule motion in the order of centimeters per second can be detected with various MRI techniques. Thus, we need new MRI techniques with high-velocity sensitivity, such as in the order of 10 μm/s, to determine water molecule movement in the vessel wall, paravascular space, and brain parenchyma. In this paper, the authors review the previous and current concepts of CSF motion in the central nervous system using various MRI techniques.</p>
収録刊行物
-
- Neurologia medico-chirurgica
-
Neurologia medico-chirurgica 59 (4), 133-146, 2019
一般社団法人 日本脳神経外科学会