Cerebellar Cortical Degeneration in a Cross-Breed Calf

  • ANRAKU Mizuki
    Obihiro University of Agriculture and Veterinary Medicine
  • UESAKA Karin
    Obihiro University of Agriculture and Veterinary Medicine United Graduate School of Veterinary Sciences, Gifu University
  • FUJII Sakiko
    Obihiro University of Agriculture and Veterinary Medicine
  • KOYAMA Kenji
    Obihiro University of Agriculture and Veterinary Medicine United Graduate School of Veterinary Sciences, Gifu University
  • KOBAYASHI Yoshiyasu
    Obihiro University of Agriculture and Veterinary Medicine United Graduate School of Veterinary Sciences, Gifu University
  • INOKUMA Hisashi
    Obihiro University of Agriculture and Veterinary Medicine United Graduate School of Veterinary Sciences, Gifu University

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Other Title
  • 交雑種子牛に発生した小脳皮質変性症の1症例
  • コウザツシュ コウシ ニ ハッセイ シタ ショウノウ ヒシツ ヘンセイショウ ノ 1 ショウレイ

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Abstract

<p>A male cross-breed (Japanese black x Holstein-Friesian) calf exhibited chronic progressive abnormalities in gait, difficulty standing, and shaking, and had a wide stance in the standing position soon after birth. At 68 days old, the calf clearly exhibited consciousness but manifested astasia. Some cerebellar anomalies were suspected based on this history and clinical findings, although there were no obvious gross lesions in the brain at necropsy. Based on the histopathological findings of degeneration/loss of Purkinje cells and axonal swelling in the cerebellum, a diagnosis was given of cerebellar cortical degeneration. Most clinical cases of cerebellar cortical degeneration in cattle are thought to have a hereditary background; however, the current case is a cross-breed calf, which suggests that this disease is not confined to a specific breed.</p>

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