Promotion of Tissue Healing and Regeneration with Low-Reactive Level Laser Therapy Using Diode Lasers in Dental Field: Review of Basic and Clinical Research

• Mikami Risako

  Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)

• Mizutani Koji

  Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)

• Aoki Akira

  Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)

• Noda Masahiro

  Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU) Tsudanuma Olive Dental Clinic

• Ejiri Kenichiro

  Eji Dental Clinic

• Izumi Yuichi

  Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU) Professor emeritus, Tokyo Medical and Dental University (TMDU) Southern TOHOKU General Hospital

Bibliographic Information

Other Title

• 歯科領域における半導体レーザーを用いたLow-Reactive Level Laser Therapyによる組織の治癒・再生の促進―基礎及び臨床研究のレビュー―

Abstract

Since the 1960’s, basic and clinical research has been conducted regarding the biostimulative effects of photobiomodulation (PBM) by means of low-reactive level laser therapy (LLLT). A number of studies have used low-level diode lasers in near-infrared to infrared wavelengths because of their high degree of tissue penetration. In the dental field, it has been shown that LLLT enhances proliferation, migration, and differentiation of gingival fibroblasts, osteoblasts, periodontal ligament cells, as well as mesenchymal stem cells in vitro. Furthermore, LLLT promoted wound healing and bone formation in vivo. Currently, less invasive and safer procedures are desired for dental treatment, especially for regenerative therapy. It is expected that PBM by means of LLLT will contribute to attaining that goal. Consequently, we have reviewed basic and clinical studies using the diode laser for LLLT, and we discuss the potential of LLLT in promoting periodontal tissue healing and regeneration.

Journal

• Nippon Laser Igakkaishi

  Nippon Laser Igakkaishi 40 (1), 15-29, 2019-04-15

  Japan Society for Laser Surgery and Medicine

Keywords

• regenerative therapy
• diode laser
• low-reactive level laser therapy (LLLT)
• wound healing
• periodontal tissue
• osteogenesis

Details

• CRID: 1390001288133545856
• NII Article ID: 130007636813
• DOI: 10.2530/jslsm.jslsm-40_0012
• ISSN: 18811639
• ISSN: 02886200
• Web Site: https://www.jstage.jst.go.jp/article/jslsm/40/1/40_jslsm-40_0012/_pdf
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed