尿・腹水から<i>Bifidobacterium breve</i>を分離した1症例  [in Japanese] A case of infection by <i>Bifidobacterium breve</i> detected in urine and ascites samples  [in Japanese]

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Abstract

<p><i>Bifidobacterium breve</i>感染症を疑う症例を経験したので報告する。症例は40歳代,男性。頻回の嘔吐が出現し全身倦怠感著明となり,意識混濁のため当院へ救急搬送された。腹水貯留,膿尿が認められ,腹水穿刺にて混濁した腹水が採取され,腹水・尿検体から分岐したグラム陽性桿菌を検出した。好気培養では菌の発育を認めず,嫌気培養した培地にのみ菌の発育を認め,質量分析と16S rRNA塩基配列の結果<i>Bifidobacterium breve</i>と同定された。入院時の尿一般検査で尿路感染症が疑われたため,入院時よりSBT/ABPC 6 g/日が投与され,全身状態は日ごとに改善し第90病日に軽快退院となった。</p>

<p>We report an adult case of infection by <i>Bifidobacterium breve</i>. A male in his 40s was admitted to our hospital because of general fatigue with frequent vomiting. He was observed to have an inflammatory response (WBC, 13,600 μ/L; CRP, 29.4 mg/dL) on admission and we speculated that this was due to continuing malnutrition or wasting condition because of low levels of albumin, cholinesterase, and triglyceride. In addition, he was observed to have remarkable electrolyte abnormality (Na, 113 mEq/L; K, 6.1 mEq/L; Cl, 67 mEq/L) and a high level of glucose at 1,203 mg/dL. He presented with purulent urine and turbid ascites, and thus a microbiological test was carried out on both urine and ascites samples. Both samples showed branched Gram-positive rods and the strain that grew was found only in anaerobic culture. The identity of the strain was not revealed by biological methods. The strain was identified as <i>Bifidobacterium breve</i> by mass analysis and 16s rRNA gene sequencing. Urine tests on admission showed leukocytes of more than 100/HPF and a score of bacteria 2+. Therefore, urinary tract infection was suspected and SBT/ABPC 6 g/day was administered. Finally, the general condition of the patient improved daily and he was discharged without symptoms on hospital day 90.</p>

Journal

  • Japanese Journal of Medical Technology

    Japanese Journal of Medical Technology 68(2), 370-375, 2019

    Japanese Association of Medical Technologists

Codes

  • NII Article ID (NAID)
    130007637219
  • Text Lang
    JPN
  • ISSN
    0915-8669
  • Data Source
    J-STAGE 
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