Journal of Health Science Total Synthesis of 3-<i>epi</i>-Juruenolide C

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Author(s)

Abstract

<p>In this study, the total synthesis of 3-<i>epi</i>-juruenolide C is achieved in 10 steps (longest linear sequence) starting from ethyl (2<i>E</i>,4<i>S</i>,5<i>S</i>)-4,5-dihydroxy-2-hexenoate. The synthetic highlights of our approach include one-pot regioselective bromination, intramolecular carbonylation using bis(triphenylphosphine)dicarbonylnickel, and face-selective hydrogenation using a homogeneous Wilkinson's catalyst.</p>

Journal

  • Chemical and Pharmaceutical Bulletin

    Chemical and Pharmaceutical Bulletin 67(6), 594-598, 2019

    The Pharmaceutical Society of Japan

Codes

  • NII Article ID (NAID)
    130007657422
  • NII NACSIS-CAT ID (NCID)
    AA00602100
  • Text Lang
    ENG
  • ISSN
    0009-2363
  • NDL Article ID
    029698583
  • NDL Call No.
    Z53-D167
  • Data Source
    NDL  J-STAGE 
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