Portal Vein Thrombosis in a Patient with Hereditary Antithrombin Deficiency
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- Setaka Tamao
- Department of Internal Medicine, Shonan East General Hospital, Japan
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- Hirano Katsuharu
- Department of Internal Medicine, Shonan East General Hospital, Japan
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- Moriya Keiichi
- Department of Internal Medicine, Shonan East General Hospital, Japan
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- Kaneko Tougen
- Department of Internal Medicine, Shonan East General Hospital, Japan
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- Morita Seie
- Department of Internal Medicine, Shonan East General Hospital, Japan
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- Shinkai Tetsu
- Department of Internal Medicine, Shonan East General Hospital, Japan
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- Morishita Eriko
- Department of Clinical Laboratory Sciences, Graduate School of Medical Science, Kanazawa University, Japan
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- Ichida Takafumi
- Department of Internal Medicine, Shonan East General Hospital, Japan
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Abstract
<p>Portal vein thrombosis (PVT) has been reported in many patients with and without liver cirrhosis. The portal vein is a rare site of thrombosis, and various conditions can predispose an individual to PVT. Among those conditions, hereditary thrombophilia has been increasingly reported recently. We herein report the case of a non-cirrhotic 30-year-old man who developed acute PVT with hereditary antithrombin deficiency. Antithrombin (AT) replacement therapy was required along with heparin. Given our experience with this case, we believe that a screening test for prothrombotic disorders, such as AT deficiency, should be considered in cases of PVT. </p>
Journal
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- Internal Medicine
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Internal Medicine 58 (12), 1733-1737, 2019-06-15
The Japanese Society of Internal Medicine