Hereditary Angioedema Type 1 with Recurrent Dizziness
-
- Ando Takashi
- Department of Neurology, Nagoya University Graduate School of Medicine, Japan
-
- Torii Ryouta
- Department of Neurology, Kasugai Municipal Hospital, Japan
-
- Kazuta Tomoyuki
- Department of Neurology, Kasugai Municipal Hospital, Japan
-
- Endo Toshihiro
- Department of Neurology, Kasugai Municipal Hospital, Japan
-
- Araki Amane
- Department of Neurology, Kasugai Municipal Hospital, Japan
-
- Horiuchi Takahiko
- Department of Internal Medicine, Kyushu University Beppu Hospital, Japan
-
- Terao Shinichi
- Department of Neurology, Kasugai Municipal Hospital, Japan
-
- Katsuno Masahisa
- Department of Neurology, Nagoya University Graduate School of Medicine, Japan
Search this article
Abstract
<p>A 41-year-old woman presented with recurrent dizziness. After an attack of dizziness, she felt edematous sensations in her hands. However, according to photographs taken during the attack, the edema on the back of the patient's hands and fingers appeared mild. Laboratory examinations revealed a low C4 and C1 inhibitor (INH) activity. A direct sequencing analysis of C1INH revealed a pathogenic gene mutation. Based on these results, she was diagnosed with hereditary angioedema (HAE) type 1. These findings indicate that HAE can cause recurrent dizziness, and it should therefore be included in the differential diagnosis in patients with recurrent neurologic symptoms, even in the absence of severe edema. </p>
Journal
-
- Internal Medicine
-
Internal Medicine 58 (13), 1961-1963, 2019-07-01
The Japanese Society of Internal Medicine
