The Usefulness of Video Capsule Endoscopy in Evaluating Gastrointestinal Manifestations of Immunoglobulin A Vasculitis
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- Tanaka Tomoko
- Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Japan
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- Hiramatsu Katsushi
- Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Japan
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- Saito Yasushi
- Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Japan
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- Nosaka Takuto
- Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Japan
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- Takahashi Kazuto
- Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Japan
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- Naito Tatsushi
- Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Japan
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- Ofuji Kazuya
- Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Japan
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- Matsuda Hidetaka
- Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Japan
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- Ohtani Masahiro
- Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Japan
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- Nemoto Tomoyuki
- Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Japan
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- Suto Hiroyuki
- Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Japan Department of Gastroenterology, Fukui Katsuyama General Hospital, Japan
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- Nakamoto Yasunari
- Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Japan
抄録
<p>Objective Immunoglobulin (Ig) A vasculitis (IgAV) is a systemic vasculitis characterized by purpura and gastrointestinal involvement showing abdominal pain that usually occurs after the emergence of purpura. Criteria for evaluating gastrointestinal manifestations of IgAV are unavailable at present, so we conducted a study to investigate the usefulness of video capsule endoscopy (VCE) for detecting gastrointestinal manifestations of IgAV. </p><p>Methods The clinical data of 10 patients who underwent VCE for IgAV at our hospital from 2012 to 2017 were collected. Nine patients underwent esophagogastroduodenoscopy, and five underwent colonoscopy. We compared the endoscopic severity determined by VCE to the findings of esophagogastroduodenoscopy and colonoscopy. </p><p>Results The rates of positive findings of esophagogastroduodenoscopy, VCE, and colonoscopy were 56%, 100%, and 80%, respectively. In 70% of cases, the most severe gastrointestinal findings were detected by VCE. VCE was performed on average 16.8 days after the emergence of purpura, and in 8 of 10 patients, its result triggered the initiation of steroid therapy or the control of the steroid dose. </p><p>Conclusion VCE is very useful for confirming gastrointestinal involvement in IgAV and may be used to determine the timing of steroid therapy initiation. We recommend performing VCE when IgAV is suspected in patients with gastrointestinal symptoms. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 58 (14), 1979-1985, 2019-07-15
一般社団法人 日本内科学会