Cycloartenyl Ferulate and β-Sitosteryl Ferulate - Steryl Ferulates of γ-Oryzanol - Suppress Intracellular Reactive Oxygen Species in Cell-based System

• Yasuda Shusuke

  Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine

• Sowa Yoshihiro

  Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine

• Hashimoto Hiroyuki

  Tsuno Food Industrial Co., Ltd.

• Nakagami Takuya

  Tsuno Food Industrial Co., Ltd.

• Tsuno Takuo

  Tsuno Food Industrial Co., Ltd.

• Sakai Toshiyuki

  Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine

Abstract

γ-Oryzanol is a naturally occurring component of rice bran and consists of various steryl ferulates. The antioxidant activities of γ-oryzanol have mostly been demonstrated in cell-free systems. Therefore, we determined whether steryl ferulate of γ-oryzanol suppress spontaneous intracellular reactive oxygen species (ROS) in cell-based systems. We found that cycloartenyl ferulate and β-sitosteryl ferulate suppressed spontaneous intracellular ROS in a similar way to N-acetylcysteine and α-tocopherol.

Journal

• Journal of Oleo Science

  Journal of Oleo Science 68 (8), 765-768, 2019

  Japan Oil Chemists' Society

Keywords

• γ-oryzanol
• cycloartenyl ferulate
• β-sitosteryl ferulate
• intracellular reactive oxygen species

Details

• CRID: 1390001288155554816
• NII Article ID: 130007686318
• NII Book ID: AA11503337
• DOI: 10.5650/jos.ess19054
• ISSN: 13473352
• ISSN: 13458957
• NDL BIB ID: 029816520
• PubMed: 31292340
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I029816520
• Web Site: https://www.jstage.jst.go.jp/article/jos/68/8/68_ess19054/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2020156140
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed