Anaphylactic Shock in the Operating Room

• TAKAZAWA Tomonori

  Intensive Care Unit, Gunma University Hospital

Bibliographic Information

Other Title

• 手術室発症のアナフィラキシーショック

Abstract

Although anaphylactic shock that occurs in the operating room is infrequent, it has to be dealt with promptly and appropriately because it is life-threatening if mishandled. Major causative agents are neuromuscular blocking agents and their antagonists and antibiotics. In addition to clinical symptoms, measurement of histamine and tryptase concentration in blood is useful for diagnosis. The first choice of drug treatment is adrenaline. Although the skin test is the gold standard for identifying causative agents, basophil activation tests that can be performed in vitro are promising tests. It is the anesthesiologist’s responsibility to identify the cause of the anaphylaxis since the patient may be at risk for anaphylaxis recurrence in the next surgery if the causative agent is left unidentified.

Journal

• THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA

  THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA 39 (4), 408-414, 2019-07-15

  THE JAPAN SOCIETY FOR CLINICAL ANESTHESIA

Keywords

• Neuromuscular blocking agent
• Sugammadex
• Skin test
• Basophil activation test

Details

• CRID: 1390001288155399936
• NII Article ID: 130007686848
• DOI: 10.2199/jjsca.39.408
• ISSN: 13499149
• ISSN: 02854945
• Web Site: https://www.jstage.jst.go.jp/article/jjsca/39/4/39_408/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2019314418
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed