Electrocardiographic Criteria of Right Ventricular Hypertrophy in Patients with Chronic Thromboembolic Pulmonary Hypertension after Balloon Pulmonary Angioplasty
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- Yokokawa Tetsuro
- Department of Cardiovascular Medicine, Fukushima Medical University, Japan Department of Pulmonary Hypertension, Fukushima Medical University, Japan
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- Sugimoto Koichi
- Department of Cardiovascular Medicine, Fukushima Medical University, Japan Department of Pulmonary Hypertension, Fukushima Medical University, Japan
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- Nakazato Kazuhiko
- Department of Cardiovascular Medicine, Fukushima Medical University, Japan
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- Misaka Tomofumi
- Department of Cardiovascular Medicine, Fukushima Medical University, Japan Department of Advanced Cardiac Therapeutics, Fukushima Medical University, Japan
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- Oikawa Masayoshi
- Department of Cardiovascular Medicine, Fukushima Medical University, Japan
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- Kobayashi Atsushi
- Department of Cardiovascular Medicine, Fukushima Medical University, Japan
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- Yoshihisa Akiomi
- Department of Cardiovascular Medicine, Fukushima Medical University, Japan Department of Advanced Cardiac Therapeutics, Fukushima Medical University, Japan
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- Yamaki Takayoshi
- Department of Cardiovascular Medicine, Fukushima Medical University, Japan
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- Kunii Hiroyuki
- Department of Cardiovascular Medicine, Fukushima Medical University, Japan
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- Ishida Takafumi
- Department of Cardiovascular Medicine, Fukushima Medical University, Japan
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- Takeishi Yasuchika
- Department of Cardiovascular Medicine, Fukushima Medical University, Japan
抄録
<p>Objective Chronic thromboembolic pulmonary hypertension (CTEPH) is a progressive disease that leads to right-sided heart failure with electrocardiographic abnormalities. There are only a few reports about the effects of balloon pulmonary angioplasty for CTEPH on the electrocardiographic criteria of right ventricular hypertrophy. To determine the effect of balloon angioplasty on electrocardiography in patients with CTEPH. </p><p>Methods We evaluated electrocardiograms in 19 patients (mean age, 64±10 years) who underwent balloon pulmonary angioplasty. </p><p>Results We compared the hemodynamic parameters after balloon pulmonary angioplasty. The mean pulmonary artery pressure was decreased (p<0.001), and the cardiac index was increased (p=0.025) after balloon pulmonary angioplasty. The level of brain natriuretic peptide was decreased (p=0.001) after balloon pulmonary angioplasty (p<0.001). We applied 15 criteria for right ventricular hypertrophy to the patients, according to the American Heart Association recommendations of the electrocardiogram, after balloon pulmonary angioplasty. Among the criteria, the numbers of patients who met the criteria of deep S in V6 (p=0.005) and max R in V1, 2+max S in I, aVL-S in V1 (p=0.046) were significantly decreased after balloon pulmonary angioplasty. The mean numbers regarding the right ventricular hypertrophic criteria in each patient were significantly decreased after balloon pulmonary angioplasty (4.8±2.6 to 3.1±2.5, p=0.003). </p><p>Conclusion In addition to improvement in hemodynamics, improvement in right ventricular hypertrophy was also observed using the electrocardiographic criteria in patients with CTEPH after balloon pulmonary angioplasty, suggesting that we should pay more attention to these changes. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 58 (15), 2139-2144, 2019-08-01
一般社団法人 日本内科学会
